Minimally Invasive Transbronchial Diagnosis and Therapeutics in Lung Cancer
Many lung tumors develop in areas that are difficult to reach using conventional tools. Our laboratory is developing advanced bronchoscopic technologies that allow clinicians to diagnose and treat lung cancer through the natural airways, reducing the need for invasive procedures while improving precision and patient outcomes.
Scanning Fiber Endoscope (SFE)
Finding lung cancer earlier begins with seeing more. Scanning fiber endoscopy (SFE) is a next-generation imaging technology that delivers ultra-high-resolution video through an ultrathin (~1 mm) flexible endoscope. Small enough to navigate the deepest regions of the lung, SFE overcomes many of the limitations of conventional bronchoscopes and allows clinicians to visualize areas that were previously inaccessible.
Why it matters: Earlier detection of small and peripheral lung cancers can increase treatment options and improve patient outcomes.
Transbronchial Therapy (RFA, PDT, PTT)
Our lab is developing minimally invasive therapies that selectively destroy cancer cells while preserving healthy lung tissue. These approaches, including photodynamic therapy (PDT), photothermal therapy (PTT), and other energy-based treatments, can be delivered directly through the airways, providing targeted treatment with minimal disruption to surrounding tissue.
Beyond local tumor destruction, these therapies may also stimulate anti-tumor immune responses capable of helping the body recognize and fight cancer throughout the body.
Why it matters: Targeted therapies have the potential to reduce treatment-related side effects while improving long-term cancer control.
From Bench to Bedside: Medical Device Development
Innovation only makes a difference when it reaches patients. Our laboratory works closely with engineers and clinicians to translate new technologies from the research bench into the operating room.
One example is OK Fibre, where we are developing specialized fibre-optic instruments that allow surgeons to perform precise laser procedures while visualizing the treatment site in real time, even within the peripheral regions of the lung.
Why it matters: By bringing innovative devices into clinical practice, we aim to expand treatment options and make minimally invasive care available to more patients.
